Oral Melanotic Macule MEDizzy Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome melanotic macule by joud aljuhani on Prezi Mucosal melanocytic macules A collection of resources for RACGP exams Next Gen GP Text Book live webinars AKT and KFP questions